MICCAI 2006 Workshop
From Statistical Atlases to Personalized Models:
Understanding Complex Diseases in Populations and Individuals
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This MICCAI 2006 workshop will feature a discussion of recent advances in statistical atlases for biomedical research as well as in image-based physiological modeling and simulation for diagnosis and treatment design. These areas are already playing and will continue to play an increasing role in biomedical research, diagnosis and treatment delivery. Over the last decade we have observed a spur of research efforts and funding directed toward the construction of populational anatomical and functional statistical atlases of several organs to underpin modern investigation into complex diseases. Brain atlases, for instance, are currently a standard tool in neuroimaging studies targeted to quantify differences among and understand factors present in subjects with schizophrenia and Alzheimer's disease, et cetera. These atlases allow analyzing population differences in morphology and function as observed through modern imaging techniques. Similar efforts have more recently been started in building atlases in the cardiovascular domain or the cerebral vasculature. |
A second thread of research has more recently targeted the construction of image-based modeling and simulation tools for personalized diagnosis, risk assessment, and customized treatment design. The convergence of computational imaging and computational physiology can be the basis for new virtual imaging modalities and also for in-silico understanding of complex diseases. The former can provide tools for extracting anatomical information, measuring personalized boundary conditions, and estimating material parameters from biomedical signals and images. The latter will contribute with models of the biophysical processes taking place at various observational levels and will pave the way for making predictions and exploring alternative treatment strategies. The workshop will stimulate contributions at the cross-road of physics, biology, physiology, biomedicine, applied mathematics, computer science and engineering, all of which with clear connections to computational imaging. |
Contributions are invited in – but not limited to – the following areas:
Computational Atlases of Anatomy and Function
- Atlas strategies: probabilistic, deformable, deformation- and density-based atlases
- Methodological underpinnings: data normalization, registration, fusion, and visualization aspects
- Statistical underpinnings: hypothesis testing and inference from population atlases, information fusion
- Mathematical underpinnings: shape and deformation theory and analysis and pattern extraction
- Exploitation of computational atlases in specific diseases
Personalized Physical Models and Simulation
- Virtual imaging techniques: imaging through personalized simulation
- Methods for image-based, non-invasive and in-vivo physiological measurements
- Methods for signal- and image-based parameter estimation of biophysical models
- Multi-scale modeling/simulation integrating molecular, structural and functional imaging
- Success stories in exploitation of simulation tools for diagnosis and therapy design
- Methods for gaining understanding of complex diseases through simulation of biophysical phenomena
- Tools for optimizing treatment design and delivery through subject-specific modeling and simulation
- Evaluation of simulation techniques with experimental and outcome data
Venue and Registration
The workshop will take place at the IT University of Copenhagen, October 6th 2006.Registration will be handled by the MICCAI 2006 registration process.
Important Dates
- Deadline for paper submission: May 1st 2006
- Notification of acceptance: July 1st 2006
- Deadline for camera-ready copy: August 15th 2006
- Workshop: October 6th 2006
Workshop Chairs
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Alejandro Frangi Ramón y Cajal Research Fellow, Ph.D. Computational Imaging Lab Pompeu Fabra University Barcelona, Spain alejandro.frangi 'at' upf.edu |
Hervé Delingette Research Director, Ph.D. INRIA - Project EPIDAURE Sophia-Antipolis, France Herve.Delingette 'at' inria.fr |
Mikkel B. Stegmann Assistant Professor, Ph.D. Informatics and Mathematical Modelling Technical University of Denmark Kgs. Lyngby, Denmark mbs 'at' imm.dtu.dk |
Program overview
| 8:00 | - | 9:00 | Registration |
| 8:45 | - | 9:00 | Workshop Opening |
| 9:00 | - | 9:40 | Invited Lecture: Computational Hemodynamics and Vascular Disease: From Pretty Pictures to Hypothesis Testing. David Steinmann. |
| 9:40 | - | 10:40 | Physiological modelling, simulation and integrative perspectives |
| 10:40 | - | 11:00 | Coffee break & Poster session: Methods |
| 11:00 | - | 12:00 | Statistical Atlases of Structure and Function I: Oncology |
| 12:00 | - | 13:30 | Lunch |
| 13:30 | - | 14:10 | Invited Lecture: TBD |
| 14:10 | - | 15:10 | Statistical Atlases of Structure and Function II: Neurology |
| 15:10 | - | 15:30 | Coffee break & Poster session: Applications |
| 15:30 | - | 16:30 | Statistical Atlases of Structure and Function III: Cardiology |
| 16:30 | - | 16:45 | Adjourn |
Download program
Detailed pdf versionInstructions for Authors
We welcome submission of workshop papers in the following format:- A PDF file containing 2 - 4 pages in the A4 format (21 x 29.7 cm or 8.27 x 11.69 inches)
- Font sizes, margins, et cetera should conform to this sample paper
Anonymity Guidelines
The paper will be reviewed in double-blind fashion (authors and reviewers have no information about the other). The authors thus have to ensure that their submitted document is anonymous by complying with the following guidelines:
- Author and institutional information needs to be removed from the author list on the title page, as well as on all paper headers.
- Clues directly identifying any of the authors need to be removed from the main text.
- Every reference to work by the authors must be made anonymous in one of the following alternative ways:
- References to other papers by the same authors are listed as "Anonymous" (with no other information) in the bibliography.
- Work by the same authors that appears on mainstream and readily available publications is cited in the third person, provided that nothing in the referencing can be traced to the identity of the authors.
- For instance, "In [5], Hello and Goodbye have proposed ..." is acceptable, whereas "In [5], we have proposed..." is not, when reference [5] is listed as "IEEE Trans. PAMI,6(6):721-741, November 1984.
- Also, "In [5], Muller and Doe have proposed ..." is not acceptable if [5] is listed as "in press", or, say, "North-Western New South Wales Symposium on Computer Vision, 1993" (no offense to North-Western New South Welsh).