Identifying Modular Relations In Complex Brain Networks

Kasper Winther Andersen, Morten Mørup, Hartwig Siebner, Kristoffer Hougaard Madsen, Lars Kai Hansen

AbstractWe evaluate the infinite relational model (IRM) against two simpler alternative nonparametric Bayesian models for identifying structures in multi subject brain networks. The models are evaluated for their ability to predict new data and infer reproducible structures. Prediction and reproducibility are measured within the data driven NPAIRS split-half framework. Using synthetic data drawn from each of the generative models we show that the IRM model outperforms the two competing models when data contain relational structure. For data drawn from the other two simpler models the IRM does not overfit and obtains comparable reproducibility and predictability. For resting state functional magnetic resonance imaging data from 30 healthy controls the IRM model is also superior to the two simpler alternatives, suggesting that brain networks indeed exhibit universal complex relational structure in the population.
KeywordsInfinite Relational Model, Complex Networks, fMRI
TypeConference paper [With referee]
ConferenceMachine Learning for Signal Processing (MLSP), 2012 IEEE International Workshop on
Year2012    pp. 1-6
ISBN / ISSN1551-2541
Electronic version(s)[pdf]
Publication link
BibTeX data [bibtex]
IMM Group(s)Intelligent Signal Processing

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