@CONFERENCE\{IMM2017-06972, author = "T. S. Alstr{\o}m and M. N. Schmidt and T. Rindzevicius and A. Boisen and J. Larsen", title = "A Pseudo-Voigt Component Model for High-Resolution Recovery of Constituent Spectra in Raman Specttroscopy", year = "2017", month = "mar", keywords = "Raman Spectroscopy, Non-negative matrix factorization (NMF), Bayesian Modeling, Pseudo-Voigt, Multivariate Curve Resolution (MCR)", booktitle = "International Conference on Acostics Speech and Signal Processing", volume = "", series = "", editor = "", publisher = "{IEEE} Press", organization = "", address = "", url = "http://www2.compute.dtu.dk/pubdb/pubs/6972-full.html", abstract = "Raman spectroscopy is a well-known analytical technique for identifying and analyzing chemical species. Since Raman scattering is a weak effect, surface-enhanced Raman spectroscopy (SERS) is often employed to amplify the signal. {SERS} signal surface mapping is a common method for detecting trace amounts of target molecules. Since the method yields large amounts of data and, in the case of very low concentrations, low signal-to-noise (SNR) ratio, ability to extract relevant spectral features is crucial. We propose a pseudo- Voigt model as a constrained source separation model, that is able to directly and reliably identify the Raman modes, with performance is similar to the state of the art non-negative matrix factorization approach. The model is a step towards enabling the use of {SERS} in detection of trace amounts of molecules in real-life settings." }