@MISC\{IMM2018-07118,
    author       = "C. F. Theisen",
    title        = "Data analysis of the link between magnesium in drinking water and mortality - with specific focus on cardiovascular diseases",
    year         = "2018",
    publisher    = "Technical University of Denmark, Department of Applied Mathematics and Computer Science",
    address      = "Richard Petersens Plads, Building 324, {DK-}2800 Kgs. Lyngby, Denmark, compute@compute.dtu.dk",
    note         = "Supervisor: Bjarne Kj{\ae}r Ersb{\o}ll, bker@dtu.dk. External supervisors: Annette Kj{\ae}r Ersb{\o}ll, Kirstine Wodschow",
    url          = "http://www.compute.dtu.dk/English.aspx",
    abstract     = "The association between magnesium in drinking water and the risk of cardiovascular death has been examined in many studies but never in a Danish context prior to this project. Some evidence of a protective effect of drinking water rich in magnesium is found in these studies. In this epidemiological study, register based data is used along with water samples taken during the past 37 years. The study is designed as a cohort study with a 10-year study period (2005-2014) and includes the entire Danish population aged 30 or more. A Poisson regression model for incidence rates was used to assess the association and included confounders on age, gender, cohabitation and family income as well as adjustment for calendar year. The results showed a significant protective effect of magnesium in drinking water on ischemic heart disease (IHD) and particularly acute myocardial infarct (AMI). The 20\% least  exposed (<6:65 mg/l), had an increased risk of 24\% of dying from {AMI} compared to the 20\% most exposed (> 21:9 mg/l). However, no association was found between the level of magnesium in drinking water and overall cardiovascular death or death from stroke. Further extensive sensitivity analysis has to be carried out to confirm the found association."
}