A Unifying model of perfusion and motion applied to reconstruction of sparsely sampled free-breathing myocardial perfusion MRI

A Unifying model of perfusion and motion applied to reconstruction of sparsely sampled free-breathing myocardial perfusion MRI
Henrik Pedersen, Hildur Olafsdottir, Rasmus Larsen, Henrik B. W. Larsson
Abstract	The clinical potential of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is currently limited by respiratory induced motion of the heart. This paper presents a unifying model of perfusion and motion in which respiratory motion becomes an integral part of myocardial perfusion quantification. Hence, the need for tedious manual motion correction prior to perfusion quantification is avoided. In addition, we demonstrate that the proposed framework facilitates the process of reconstructing DCEMRI from sparsely sampled data in the presence of respiratory motion. The paper focuses primarily on the underlying theory of the proposed framework, but shows in vivo results of respiratory motion correction and simulation results of reconstructing sparsely sampled data.
Keywords	Dynamic MRI, myocardial perfusion,
Type	Conference paper [With referee]
Conference	Proceedings of IEEE International Symposium on Biomedical Imaging: From Nano to Macro 2010
Editors	Erik Meijering and Wiro Niessen
Year	2010 Month May pp. 752-755
Electronic version(s)	[pdf]
BibTeX data	[bibtex]
IMM Group(s)	Image Analysis & Computer Graphics