Optimization and Simulation in Drug Development - Review and Analysis |
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| Abstract | We give a review of pharmaceutical R&D and mathematical simulation and optimization methods used to support decision making within the pharmaceutical development process.
The complex nature of drug development is pointed out through a description of the various phases of the pharmaceutical development process. A part of the paper is dedicated to the use of simulation techniques to support clinical trials. The paper ends with a section describing portfolio modelling methods in the context of the pharmaceutical industry. |
| Keywords | Pharmaceutical R&D, Drug Discovery and Development, Modelling and simulation, Clinical Trial Simulation Portfolio optimization |
| Type | Technical report |
| Year | 2003 |
| Publisher | Informatics and Mathematical Modelling, Technical University of Denmark, DTU |
| Address | Richard Petersens Plads, Building 321, DK-2800 Kgs. Lyngby |
| Series | IMM-Technical report-2003-26 |
| Electronic version(s) | [ps] |
| BibTeX data | [bibtex] |
| IMM Group(s) | Operations Research |