The lectures are given in building 321, room 033, on Thursdays from 1 pm – 2.30 pm (approximately). The computer exercises take place immediately after the lectures in the same room. Terminals are reserved until 5 pm; a teaching assistant will be present. You may also use the terminals outside this time-window, provided you can find a terminal that is not occupied. The computer exercises are on the topic of last week’s lecture. The computer exercises should be carried out in groups of 2-3.
Lecture notes and exercise texts and materials are available through campusnet (one week in advance - as a rule).
For each subject considered in the course an exercise is carried out and an exercise report must be prepared and handed in. The course examination consists of an oral examination in the course topics based on the course theory and exercise reports. The oral examination will be held on Monday, December 12th.
This is a 5 ECTS point course corresponding to a work load of 8-10 hours work per week and most of this time is used to implement the image analysis models in the exercises. Some of the algorithms are complicated and the computations can be time-consuming. You can only understand these algorithms fully by implementing them, so that you can test the effect of varying data and parameters. Hence a successful completion of the course (and exam) requires that your implementation works and that you demonstrate a good understanding of the strengths and weaknesses of the models.
| No. | Date | Lecturer | Lecture | Exercise |
| 1 | 1 Sep | kvle |
Introduction; Fitting of image functions Linear basis function models; maximum likelihood estimation and least squares; regularization; image smoothing; image interpolation |
No exercise |
| 2 | 8 Sep | kvle | Landmark based registration | MR bias field correction |
| 3 | 15 Sep | ksjo |
Intensity based methods for registration Sum-of-squared differences; correlation; mutual information; principal axis transform |
Landmark-based registration |
| 4 | 22 Sep | jsv | EXCURSION: Danish Research Center for Magnetic Resonance (DRCMR) | No exercise |
| 5 | 29 Sep | kvle | Non-linear deformations | Mutual information based registration |
| 6 | 6 Oct | rl | Surface based registration | non-linear intensity-based registration |
| 7 | 13 Oct | rl |
surface-based segmentation Active contour model; dynamic programming |
non-linear intensity-based registration (cont.) |
| 8 | 27 Oct | kvle |
Voxel-based segmentation I Gaussian mixture model; Markov random field priors; mean-field approximation |
Surface-based registration |
| 9 | 3 Nov | kvle |
Voxel-based segmentation II Expectation-Maximization algorithm; MR bias field correction |
Dynamic programming |
| 10 | 10 Nov | kvle |
Atlases Reference templates; group-wise registration; probabilistic atlases; label propagation |
Brain tumor segmentation |
| 11 | 17 Nov | Tron Darvann, 3Dlab | EXCURSION: 3D laboratory. School of Dentistry | No exercise |
| 12 | 24 Nov | kvle | Validation of segmentation methods | Expectation-Maximization algorithm |
| 13 | 1 Dec |
Michael Grunkin,Visiopharm kvle |
Entrepreneurship in the life sciences and wrap up | Exercise catch-up |